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Article

Genome-wide methylation profiling of the bronchial mucosa of asthmatics: relationship to atopy

24 Mar 2013

Abstract excerpt

BACKGROUND: Asthma is a common respiratory disease that is characterized by bronchial hyperresponsiveness and airway obstruction due to chronic airway inflammation. Atopic asthma is a typical IgE-mediated disease in which the enhanced production of IgE is driven by the activation of Th2 cells, which release a distinct pattern of cytokines, including interleukin 4 (IL4) and IL3, in response to specific antigen...

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PMID: 23521807
DOI: 10.1186/1471-2350-14-39

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