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Article

FGF2 deficit during development leads to specific neuronal cell loss in the enteric nervous system.

Histochemistry and cell biology - 1 Jan 2013

Hagl Cornelia Irene, Wink Elvira, Scherf Sabrina, Heumüller-Klug Sabine, Hausott Barbara, Schäfer Karl-Herbert

Abstract excerpt

The largest part of the peripheral nervous system is the enteric nervous system (ENS). It consists of an intricate network of several enteric neuronal subclasses with distinct phenotypes and functions within the gut wall. The generation of these enteric phenotypes is dependent upon appropriate neurotrophic support during development. Glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth...

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Source

Identifiers

PMID: 22955838
DOI: 10.1007/s00418-012-1023-3

Genes

FGF2
GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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