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Article

Genome-scale reconstruction and analysis of the metabolic network in the hyperthermophilic archaeon Sulfolobus solfataricus.

PloS one - 1 Jan 2012

Ulas Thomas, Riemer S Alexander, Zaparty Melanie, Siebers Bettina, Schomburg Dietmar

Abstract excerpt

We describe the reconstruction of a genome-scale metabolic model of the crenarchaeon Sulfolobus solfataricus, a hyperthermoacidophilic microorganism. It grows in terrestrial volcanic hot springs with growth occurring at pH 2-4 (optimum 3.5) and a temperature of 75-80°C (optimum 80°C). The genome of Sulfolobus solfataricus P2 contains 2,992,245 bp on a single circular chromosome and encodes 2,977 proteins and a...

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PMID: 22952675
DOI: 10.1371/journal.pone.0043401
PMCID: PMC3432047

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