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Article

Mutational screening of SF1 and WNT4 in Tunisian women with premature ovarian failure.

Gene - 10 Nov 2012

Lakhal Besma, Ben-Hadj-Khalifa Sonia, Bouali Nouha, Braham Rim, Hatem Elghezal, Saad Ali

Abstract excerpt

BACKGROUND: WNT4 and SF1 genes play an important role in ovarian development. They constitute coherent candidate genes associated with premature ovarian failure (POF) pathogenesis. METHODS: We sequenced the coding region of WNT4 and SF1 in 55 Tunisian women with POF and 100 healthy controls. RESULTS: We identified a synonymous variation in WNT4 (c.99G>A, p.Ser33Ser) and a substitution (c.G437C) in SF1 gene...

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Source

Identifiers

PMID: 22951804
DOI: 10.1016/j.gene.2012.08.007

Genes

WNT4
GCG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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