Article
Proteomic Analysis Reveals New Cardiac-Specific Dystrophin-Associated Proteins
24 Aug 2012
Abstract excerpt
Mutations affecting the expression of dystrophin result in progressive loss of skeletal muscle function and cardiomyopathy leading to early mortality. Interestingly, clinical studies revealed no correlation in disease severity or age of onset between cardiac and skeletal muscles, suggesting that dystrophin may play overlapping yet different roles in these two striated muscles. Since dystrophin serves as a...
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