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Article

Clonal expansion of both modern and ancient genotypes of Mycobacterium tuberculosis in southern Taiwan.

PloS one - 1 Jan 2012

Chang Jia-Ru, Chen Yih-Yuan, Huang Tsi-Shu, Huang Wei-Feng, Kuo Shu-Chen, Tseng Fan-Chen, Su Ih-Jen, Lin Chien-Hsing, Chen Yao-Shen, Sun Jun-Ren, Chiueh Tzong-Shi, Dou Horng-Yunn

Abstract excerpt

We present the first comprehensive analysis of Mycobacterium tuberculosis isolates circulating in the Kaohsiung region of southern Taiwan. The major spoligotypes found in the 224 isolates studied were Beijing lineages (n = 97; 43.3%), EAI lineages (n = 72; 32.1%) and Haarlem lineages (n = 18; 8.0%). By 24 MIRU-VNTR typing, 174 patterns were identified, including 24 clusters of 74 isolates and 150 unique patterns....

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PMID: 22937008
DOI: 10.1371/journal.pone.0043018
PMCID: PMC3427295

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