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Article

A replication study on proposed candidate genes in Ménière's disease, and a review of the current status of genetic studies.

International journal of audiology - 1 Nov 2012

Hietikko Elina, Kotimäki Jouko, Okuloff Annaleena, Sorri Martti, Männikkö Minna

Abstract excerpt

OBJECTIVE: Multiple candidate genes have been presented for Ménière's disease (MD), but to date no positive replications have been reported. We review here all the previously proposed candidate genes for MD and report our results on the analysis of six such genes, AQP2, KCNE1, KCNE3, HCFC1, COCH, and ADD1. STUDY SAMPLE: A well-defined sample set of 38 sporadic and 21 familial Finnish MD patients. DESIGN: Mutation...

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Source

Identifiers

PMID: 22934933
DOI: 10.3109/14992027.2012.705900

Genes

ADD1
AQP2
COCH
HCFC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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