Article
Ménière's disease is associated with single nucleotide polymorphisms in the human potassium channel genes, KCNE1 and KCNE3.
ORL; journal for oto-rhino-laryngology and its related specialties - 1 Jan 2005
Doi Katsumi, Sato Takashi, Kuramasu Toshihiro, Hibino Hiroshi, Kitahara Tadashi, Horii Arata, Matsushiro Naoki, Fuse Yuka, Kubo Takeshi
Abstract excerpt
Although the bases for both the sporadic and inherited forms of Ménière's disease (MD) remain undefined, it is likely to be multifactorial, one of the factors being a genetic predisposition. Recently, genetic association studies on complex diseases have become very popular and most of them are case-control studies using single nucleotide polymorphisms (SNPs) as markers. Mutations/polymorphisms in KCNE potassium...
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