Article
Multiparameter flow cytometry and bioanalytics for B cell profiling in systemic lupus erythematosus.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Kaminski Denise A, Wei Chungwen, Rosenberg Alexander F, Lee F Eun-Hung, Sanz Ignacio
Abstract excerpt
B lymphocyte involvement in systemic lupus erythematosus has been recognized for several decades, mainly in the context of autoantibody production. Both mouse and human studies reveal that different types of antibody responses, as well as antibody-independent effector functions can be ascribed to distinct subpopulations (subsets) of circulating B cells. Characterizing human B cell subsets can advance the field of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
