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Article

The timing of pigmentation lightening in Europeans.

Molecular biology and evolution - 1 Jan 2013

Beleza Sandra, Santos António M, McEvoy Brian, Alves Isabel, Martinho Cláudia, Cameron Emily, Shriver Mark D, Parra Esteban J, Rocha Jorge

Abstract excerpt

The inverse correlation between skin pigmentation and latitude observed in human populations is thought to have been shaped by selective pressures favoring lighter skin to facilitate vitamin D synthesis in regions far from the equator. Several candidate genes for skin pigmentation have been shown to exhibit patterns of polymorphism that overlap the geospatial variation in skin color. However, little work has...

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Source

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Identifiers

PMID: 22923467
DOI: 10.1093/molbev/mss207
PMCID: PMC3525146

Genes

KITLG
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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