Article
Skeletal effects of vitamin D supplementation in postmenopausal black women.
Calcified tissue international - 1 Nov 2012
Nieves J W, Cosman F, Grubert E, Ambrose B, Ralston S H, Lindsay R
Abstract excerpt
Black women have lower serum 25-hydroxyvitamin D (25[OH]D) levels and higher parathyroid hormone (PTH) levels than white peers but lower bone turnover, suggesting skeletal resistance to PTH. Our objective was to determine if vitamin D supplementation (1,000 IU/day) would prevent bone loss and whether vitamin D receptor (VDR) polymorphisms modify the response. We performed a 2-year randomized, controlled,...
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