Article
Vitamin D receptor gene polymorphisms modulate the skeletal response to vitamin D supplementation in healthy girls.
Bone - 1 Dec 2009
Arabi Asma, Zahed Laila, Mahfoud Ziyad, El-Onsi Lina, Nabulsi Mona, Maalouf Joyce, Fuleihan Ghada El-Hajj
Abstract excerpt
OBJECTIVES: Vitamin D receptor (VDR) gene plays an important role in bone mass regulation. We have previously shown a beneficial effect of vitamin D supplementation on bone mass in girls. This study investigated whether the musculo-skeletal response to Vitamin D was modulated by polymorphisms in VDR gene. DESIGN: Randomized placebo-controlled trial. METHODS: 179 girls (10-17 years), were randomly assigned to...
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