Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of ALDH2 Glu504Lys polymorphism on nitroglycerin response in chronic heart failure and involvement of Calcitonin Gene Related Peptide (CGRP).

International journal of clinical pharmacology and therapeutics - 1 Oct 2012

Peng Li-Ming, Chen Xiao-Ping, Sun Ji, Guo Yi-Jie, Li Ling, Mo Long, Xie Wei, Li Yuan-Jian, Yang Tian-Lun, Li Chuan-Chang

Abstract excerpt

OBJECTIVE: The aim of this study was to investigate whether the neuropeptide calcitonin gene related peptide (CGRP) contributes to nitroglycerin (GTN) response in patients with chronic heart failure (CHF) and the association with the mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys (ALDH2*2) polymorphism. METHODS: This is a 2-period, placebo-controlled clinical study. An intravenous infusion of saline...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldehyde Dehydrogenase
Share to Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcitonin Gene-Related Peptide

Share to Chronic Disease

Share to Heart Failure

Share to Hemodynamics

Share to Polymorphism, Genetic

Share to Vasodilator Agents

Source

Identifiers

PMID: 22909898
DOI: 10.5414/CP201635

Genes

ALDH2
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of ALDH2 Glu504Lys polymorphism on nitroglycerin response in chronic heart failure and involvement of Calcitonin Gene Related Peptide (CGRP).PMID 22909898Read ↗

Evidence for involvement of calcitonin gene-related peptide in nitroglycerin response and association with mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism.Semantic proximity Read ↗

The Vascular-Dependent and -Independent Actions of Calcitonin Gene-Related Peptide in Cardiovascular DiseaseSemantic proximity Read ↗

Involvement of anandamide transporter in calcitonin gene-related peptide expression stimulated by nitroglycerin and influence of ALDH2 Glu504Lys polymorphism.Semantic proximity Read ↗

Clinical Potential of Adrenomedullin Signaling in the Cardiovascular SystemSemantic proximity Read ↗

Why Do We Not Assess Sympathetic Nervous System Activity in Heart Failure Management: Might GRK2 Serve as a New Biomarker?Semantic proximity Read ↗

Relationship Between Aldehyde Dehydrogenase 2 Gene Polymorphism and Vasodilative Effect of Nitroglycerin on Coronary Arteries.Semantic proximity Read ↗

The effects of ALDH2 Glu487Lys polymorphism on vasovagal syncope patients undergoing head-up tilt test supplemented with sublingual nitroglycerinSemantic proximity Read ↗

Calcitonin Gene-Related Peptide Protects Against Cardiovascular Dysfunction Independently of Nitric Oxide In VivoSemantic proximity Read ↗

[The relationship between aldehyde dehydrogenase-2 gene polymorphisms and efficacy of nitroglycerin].Semantic proximity Read ↗

Calcitonin gene related peptide.Semantic proximity Read ↗

Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans.Semantic proximity Read ↗

Big endothelin in chronic heart failure: marker of disease severity or genetic determination?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.