Article
A functional study of nucleocytoplasmic transport signals of the EhNCABP166 protein from Entamoeba histolytica.
Parasitology - 1 Nov 2012
Uribe R, Almaraz Barrera Ma de J, Robles-Flores M, Mendoza Hernández G, González-Robles A, Hernández-Rivas R, Guillen N, Vargas M
Abstract excerpt
EhNCABP166 is an Entamoeba histolytica actin-binding protein that localizes to the nucleus and cytoplasm. Bioinformatic analysis of the EhNCABP166 amino acid sequence shows the presence of 3 bipartite nuclear localization signals (NLS) and a nuclear export signal (NES). The present study aimed to investigate the functionality of these signals in 3 ways. First, we fused each potential NLS to a cytoplasmic domain...
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