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Article

Pathway and network-based analysis of genome-wide association studies and RT-PCR validation in polycystic ovary syndrome.

International journal of molecular medicine - 1 Nov 2017

Shen Haoran, Liang Zhou, Zheng Saihua, Li Xuelian

Abstract excerpt

The purpose of this study was to identify promising candidate genes and pathways in polycystic ovary syndrome (PCOS). Microarray dataset GSE345269 obtained from the Gene Expression Omnibus database includes 7 granulosa cell samples from PCOS patients, and 3 normal granulosa cell samples. Differentially expressed genes (DEGs) were screened between PCOS and normal samples. Pathway enrichment analysis was conducted...

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Source

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Identifiers

PMID: 28949383
DOI: 10.3892/ijmm.2017.3146
PMCID: PMC5627882

Genes

ARHGAP4
ARHGAP9
LYN
RHOG
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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