Parental electrocardiographic screening identifies a high degree of inheritance for congenital and childhood nonimmune isolated atrioventricular block.

doi:10.1161/CIRCULATIONAHA.111.069161

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Article

Parental electrocardiographic screening identifies a high degree of inheritance for congenital and childhood nonimmune isolated atrioventricular block.

Circulation - 18 Sept 2012

Baruteau Alban-Elouen, Behaghel Albin, Fouchard Swanny, Mabo Philippe, Schott Jean-Jacques, Dina Christian, Chatel Stéphanie, Villain Elisabeth, Thambo Jean-Benoit, Marçon François, Gournay Véronique, Rouault Francis, Chantepie Alain, Guillaumont Sophie, Godart François, Martins Raphaël P, Delasalle Béatrice, Bonnet Caroline, Fraisse Alain, Schleich Jean-Marc, Lusson Jean-René, Dulac Yves, Daubert Jean-Claude, Le Marec Hervé, Probst Vincent

Abstract excerpt

BACKGROUND: The origin of congenital or childhood nonimmune isolated atrioventricular (AV) block remains unknown. We hypothesized that this conduction abnormality in the young may be a heritable disease. METHODS AND RESULTS: A multicenter retrospective study (13 French referral centers, from 1980-2009) included 141 children with AV block diagnosed in utero, at birth, or before 15 years of age without structural...

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PMID: 22899775
DOI: 10.1161/CIRCULATIONAHA.111.069161

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