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<scp>PAMP</scp>s and <scp>DAMP</scp>s: signal 0s that spur autophagy and immunity

14 Aug 2012

Abstract excerpt

Pathogen-associated molecular pattern molecules (PAMPs) are derived from microorganisms and recognized by pattern recognition receptor (PRR)-bearing cells of the innate immune system as well as many epithelial cells. In contrast, damage-associated molecular pattern molecules (DAMPs) are cell-derived and initiate and perpetuate immunity in response to trauma, ischemia, and tissue damage, either in the absence or...

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PMID: 22889221
DOI: 10.1111/j.1600-065x.2012.01146.x

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