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Article

Oxidative stress and apoptosis in homocystinuria patients with genetic remethylation defects.

Journal of cellular biochemistry - 1 Jan 2013

Richard Eva, Desviat Lourdes R, Ugarte Magdalena, Pérez Belén

Abstract excerpt

Oxidative stress has been described as a putative disease mechanism in pathologies associated with an elevation of homocysteine. An increased reactive oxygen species (ROS) production and apoptosis rate have been associated with several disorders of cobalamin metabolism, particularly with methylma...

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Source

Identifiers

PMID: 22887477
DOI: 10.1002/jcb.24316

Genes

MTRR
MTR
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22887477-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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