Article
Association of the miR-146aC>G, miR-149T>C, miR-196a2T>C, and miR-499A>G polymorphisms with risk of spontaneously aborted fetuses.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2012
Jeon Young Joo, Kim Su Yeoun, Rah HyungChul, Choi Dong Hee, Cha Sun Hee, Yoon Tae Ki, Lee Woo Sik, Shim Sung Han, Kim Nam Keun
Abstract excerpt
PROBLEM: The miR-196a2T>C and miR-499A>G polymorphisms have been reported to be genetic risk factors for recurrent spontaneous abortion; however, that previous study focused on the genetic analyses of pregnant women rather than aborted fetuses. Because annexin A1 is a target of miR-196a2 and is related to anti-inflammation, miR-196a2 may be immunologically important. Moreover, miR-146a, miR-149, miR-196a2, and...
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