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Time-Lapse Cleavage Rating Predicts Human Embryo Viability

17 Oct 2012

Abstract excerpt

Chronology of three consecutive mitotic events in human pre-implantation embryos was examined by time-lapse imaging. In zygotes producing well-formed and pregnancy-yielding expanded blastocysts, uniform time-patterning of cleavage clusters (c) and interphases (i) was revealed: i2=11+/-1, i3=15+/-1, i4=23+/-1 h / c2=15+/-5, c3=40+/-10, c4=55+/-15 min. Oppositely, shortened or prolonged durations of one or more...

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PMID: 22881225
DOI: 10.33549/physiolres.932287

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