A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.

doi:10.1038/mp.2012.113

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A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.

Molecular psychiatry - 1 Aug 2013

Logue M W, Baldwin C, Guffanti G, Melista E, Wolf E J, Reardon A F, Uddin M, Wildman D, Galea S, Koenen K C, Miller M W

Abstract excerpt

We describe the results of the first genome-wide association study (GWAS) of post-traumatic stress disorder (PTSD) performed using trauma-exposed white non-Hispanic participants from a cohort of veterans and their intimate partners (295 cases and 196 controls). Several single-nucleotide polymorphisms (SNPs) yielded evidence of association. One SNP (rs8042149), located in the retinoid-related orphan receptor alpha...

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PMID: 22869035
DOI: 10.1038/mp.2012.113
PMCID: PMC3494788

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RORA

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