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Article

A genome-wide association study of Alzheimer's disease using random forests and enrichment analysis.

Science China. Life sciences - 1 Jul 2012

Zou Liang, Huang Qiong, Li Ao, Wang Minghui

Abstract excerpt

Alzheimer's disease (AD) is a serious neurodegenerative disorder and its cause remains largely elusive. In past years, genome-wide association (GWA) studies have provided an effective means for AD research. However, the univariate method that is commonly used in GWA studies cannot effectively detect the biological mechanisms associated with this disease. In this study, we propose a new strategy for the GWA...

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PMID: 22864836
DOI: 10.1007/s11427-012-4343-6

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