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Article

ROCKs cause SHP-wrecks and broken hearts.

Small GTPases - 1 Jan 2000

Tandon Panna, Conlon Frank L, Taylor Joan M

Abstract excerpt

During embryogenesis, the heart is one of the first organs to develop. Its formation requires a complex combination of migration of cardiac precursors to the ventral midline coupled with the fusion of these cardiogenic fields and subsequent cellular reorganization to form a linear heart tube. A finely controlled choreography of cell proliferation, adhesion, contraction and movement drives the heart tube to loop...

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Identifiers

PMID: 22858643
DOI: 10.4161/sgtp.20960
PMCID: PMC3520883

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