Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection rates of clinically significant genomic alterations by microarray analysis for specific anomalies detected by ultrasound.

Prenatal diagnosis - 1 Oct 2012

Shaffer Lisa G, Rosenfeld Jill A, Dabell Mindy P, Coppinger Justine, Bandholz Anne M, Ellison Jay W, Ravnan J Britt, Torchia Beth S, Ballif Blake C, Fisher Allan J

Abstract excerpt

OBJECTIVE: The aim of this study is to understand the diagnostic utility of comparative genomic hybridization (CGH)-based microarrays for pregnancies with abnormal ultrasound findings. METHODS: We performed a retrospective analysis of 2858 pregnancies with abnormal ultrasounds and normal karyotypes (when performed) tested in our laboratory using CGH microarrays targeted to known chromosomal syndromes with later...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Bones
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Congenital Abnormalities

Share to Heart Defects, Congenital

Share to Holoprosencephaly

Share to Microarray Analysis

Share to Prenatal Diagnosis

Share to Ultrasonography, Prenatal

Source

Open in PubMed Open full text

Identifiers

PMID: 22847778
DOI: 10.1002/pd.3943
PMCID: PMC3509216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection rates of clinically significant genomic alterations by microarray analysis for specific anomalies detected by ultrasound.PMID 22847778Read ↗

Prenatal chromosomal microarray testing of fetuses with ultrasound structural anomalies: A prospective cohort study of over 1000 consecutive casesSemantic proximity Read ↗

The role of chromosomal microarray analysis among fetuses with normal karyotype and single system anomaly or nonspecific sonographic findingsSemantic proximity Read ↗

Chromosomal Abnormalities Detected by Chromosomal Microarray Analysis and Karyotype in Fetuses with Ultrasound AbnormalitiesSemantic proximity Read ↗

Chromosomal Microarray Analysis Results From Pregnancies With Various Ultrasonographic AnomaliesSemantic proximity Read ↗

Use of array comparative genomic hybridization for prenatal diagnosis of fetuses with sonographic anomalies and normal metaphase karyotypeSemantic proximity Read ↗

A retrospective study for diagnostic value of chromosomal microarray analysis in fetuses with high-risk prenatal indicationsSemantic proximity Read ↗

Whole‐genome microarray analysis in prenatal specimens identifies clinically significant chromosome alterations without increase in results of unclear significance compared to targeted microarraySemantic proximity Read ↗

Diagnostic performance of chromosomal microarray and whole exome sequencing in fetal structural anomalies: a single-center retrospective studySemantic proximity Read ↗

Prenatal chromosomal microarray analysis in 2466 fetuses with ultrasonographic soft markers: a prospective cohort study.Semantic proximity Read ↗

Chromosomal Microarray Analysis Results From Pregnancies With Various Ultrasonographic AnomaliesSemantic proximity Read ↗

Microarray comparative genomic hybridization in prenatal diagnosis: a reviewSemantic proximity Read ↗

Chromosomal Microarray Analysis and Karyotype Analysis for Prenatal Diagnosis of Fetuses With Abnormal Ultrasound Soft MarkersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.