Article
Prenatal chromosomal microarray analysis in 2466 fetuses with ultrasonographic soft markers: a prospective cohort study.
American journal of obstetrics and gynecology - 1 May 2021
Hu Ting, Tian Tian, Zhang Zhu, Wang Jiamin, Hu Rui, Xiao Like, Zhu Hongmei, Lai Yi, Wang He, Liu Shanling
Abstract excerpt
BACKGROUND: Soft markers are nonspecific findings detected by ultrasonography during the second trimester that are often transient and nonpathologic but may imply an increased risk of underlying fetal aneuploidy. However, large-scale prospectively stratified studies focusing on the prevalence of chromosomal aberrations, including copy number variants, in fetuses with different types of isolated soft markers have...
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