Use of array comparative genomic hybridization for prenatal diagnosis of fetuses with sonographic anomalies and normal metaphase karyotype

Abstract excerpt

OBJECTIVE: To prospectively study the addition of array comparative genomic hybridization (CGH) to the prenatal evaluation of fetal structural anomalies. METHODS: Pregnant women carrying fetuses with a major structural abnormality were recruited at the time of invasive procedure for chromosome analysis. Only women whose fetuses had a normal karyotype (n = 50) were subsequently evaluated by array CGH using one of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Fetal and Pediatric Neurological Disorders
• Share to Genomic variations and chromosomal abnormalities
• Share to Prenatal Screening and Diagnostics