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Pathogenicity and Transmissibility of North American Triple Reassortant Swine Influenza A Viruses in Ferrets

19 Jul 2012

Abstract excerpt

North American triple reassortant swine (TRS) influenza A viruses have caused sporadic human infections since 2005, but human-to-human transmission has not been documented. These viruses have six gene segments (PB2, PB1, PA, HA, NP, and NS) closely related to those of the 2009 H1N1 pandemic viruses. Therefore, understanding of these viruses' pathogenicity and transmissibility may help to identify determinants of...

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PMID: 22829764
DOI: 10.1371/journal.ppat.1002791

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