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Article

Aspergillus nidulans and Chronic Granulomatous Disease: A Unique Host–Pathogen Interaction

24 Jul 2012

Abstract excerpt

Invasive fungal infections are a major threat for patients suffering from chronic granulomatous disease (CGD), a primary immunodeficiency caused by a defect in the nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase. Interestingly, Aspergillus (Emericella) nidulans is the second most encountered mold in CGD patients, causing almost exclusively invasive infections in this specific host, and is...

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PMID: 22829648
DOI: 10.1093/infdis/jis473

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