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Article

Recombination and natural selection in hepatitis E virus genotypes.

Journal of medical virology - 1 Sept 2012

Chen Xiaoming, Zhang Qian, He Chao, Zhang Lei, Li Jinghua, Zhang Weilu, Cao Wei, Lv Yong-Gang, Liu Zhengcai, Zhang Jing-Xia, Shao Zhong-Jun

Abstract excerpt

To gain new insights into the evolutionary processes that created the genetic diversity of the hepatitis E virus (HEV), the Recombination Detection Program (RDP) and SimPlot program were employed to detect recombination events in the genome, then the fixed-effects likelihood (FEL) method was used to detect natural selection effects on viral proteins. Recombination analysis provided strong evidence for both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22825818
DOI: 10.1002/jmv.23237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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