Article
Urine TMPRSS2:ERG fusion transcript integrated with PCA3 score, genotyping, and biological features are correlated to the results of prostatic biopsies in men at risk of prostate cancer.
The Prostate - 15 Feb 2013
Cornu Jean-Nicolas, Cancel-Tassin Géraldine, Egrot Christophe, Gaffory Cécile, Haab François, Cussenot Olivier
Abstract excerpt
BACKGROUND: Detection of fusion gene TMPRSS2:ERG transcripts in urine have been recently described in order to refine urine-based detection of prostate cancer (PCa), but data its clinical impact remain scarce. We aimed at investigating the correlation of TMPRSS2:ERG, prostate cancer antigen 3 (PCA3), prostate specific antigen (PSA) density, genetic variants, and androgenic status with outcome and pathological...
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