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Article

Preliminary genetic imaging study of the association between estrogen receptor-α gene polymorphisms and harsh human maternal parenting.

Neuroscience letters - 6 Sept 2012

Lahey Benjamin B, Michalska Kalina J, Liu Chunyu, Chen Qi, Hipwell Alison E, Chronis-Tuscano Andrea, Waldman Irwin D, Decety Jean

Abstract excerpt

A failure of neural changes initiated by the estrogen surge in late pregnancy to reverse the valence of infant stimuli from aversive to rewarding is associated with dysfunctional maternal behavior in nonhuman mammals. Estrogen receptor-α plays the crucial role in mediating these neural effects of...

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Identifiers

PMID: 22819972
DOI: 10.1016/j.neulet.2012.07.016
PMCID: PMC3434869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22819972-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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