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Identification of hub genes associated with cognition in the hippocampus of Alzheimer’s Disease

1 Nov 2021

Abstract excerpt

Alzheimer’s Disease (AD) is a neurodegenerative disease featured by cognitive impairment. This bioinformatic analysis was used to identify hub genes related to cognitive dysfunction in AD. The gene expression profile GSE48350 in the hippocampus of AD patients aged >70 years was obtained from the Gene Expression Omnibus (GEO) database. A total of 96 differentially expressed genes (DEGs) were identified, and...

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PMID: 34719328
DOI: 10.1080/21655979.2021.1999549

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