Article
[Association of susceptibility to chronic rhinosinusitis with genetic polymorphisms of IL-4 and IL-10].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery - 1 Mar 2012
Zhang Mei-li, Ni Pei-hua, Cai Chang-ping, Chen Ni-jun, Wang Shi-li
Abstract excerpt
OBJECTIVE: To investigate the relationship between the promoter polymorphism of IL-4 and IL-6 and chronic rhinosinusitis (CRS). METHODS: One hundred and twenty-three patients with CRS and 239 healthy controls in Shanghai region were chosen in this study. The genotype of IL-4 gene -33T>C and -590C>T were determined using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method and the...
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