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Article

[The association between genetic polymorphisms of IL-6 and the susceptibility of chronic rhinosinusitis].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery - 1 Mar 2012

Zhang Meili, Ni Peihua, Cai Changping, Chen Nijun, Wang Shili

Abstract excerpt

OBJECTIVE: To investigate the relationship between the promoter polymorphism of IL6 (-174G > C, -572G > C and -597G > A) and chronic rhinosinusitis (CRS). METHOD: The case-control study consisted of 123 patients with CRS and 239 controls from a Chinese Han population from Shanghai. The genotypes of the subjects were determined by polymerase chain reaction-restriction fragment length polymorphism and gene...

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PMID: 22667128
DOI: 10.13201/j.issn.1001-1781.2012.05.006

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