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Article

Distinct expression pattern of claudin-6, a primitive phenotypic tight junction molecule, in germ cell tumours and visceral carcinomas.

Histopathology - 1 Dec 2012

Ushiku Tetsuo, Shinozaki-Ushiku Aya, Maeda Daichi, Morita Shigeki, Fukayama Masashi

Abstract excerpt

AIMS: This study aimed to clarify claudin-6 expression patterns in cancers. METHODS AND RESULTS: We surveyed claudin-6 expression by immunohistochemistry using tissue microarray in 860 tumours, including germ cell tumours and major carcinomas. Claudin-6 was expressed consistently in germ cell tumours (28 of 28, 100%), whereas only 64 (8%) of 832 non-germ cell tumours demonstrated claudin-6 expression. Further...

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PMID: 22803571
DOI: 10.1111/j.1365-2559.2012.04314.x

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AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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