RNA-binding protein LIN28 is a sensitive marker of ovarian primitive germ cell tumours

Abstract excerpt

AIMS: LIN28 is an RNA-binding protein that has been detected in testicular germ cell tumours (GCTs), but its status in ovarian GCTs is unknown. The aim was to determine the immunohistochemical profile of LIN28 in ovarian GCTs. METHODS AND RESULTS: Immunohistochemistry of LIN28 was performed in 110 primary and 11 metastatic ovarian GCTs. The percentage of tumour cells stained was scored as 0, 1+ (1-30% cells), 2+...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ovarian cancer diagnosis and treatment
• Share to Sperm and Testicular Function
• Share to Testicular diseases and treatments