Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion

11 Jul 2012

Abstract excerpt

Cutaneous squamous cell carcinoma (cSCC) is the second most common human cancer. Although dysregulation of microRNAs (miRNAs) is known to be involved in a variety of cancers, the role of miRNAs in cSCC is unclear. In this study, we aimed to identify tumor suppressive and oncogenic miRNAs involved in the pathogenesis of cSCC. MiRNA expression profiles in healthy skins (n = 4) and cSCCs (n = 4) were analyzed using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to MicroRNA in disease regulation
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22782903
DOI: 10.1074/jbc.m112.391243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and InvasionPMID 22782903Read ↗

miRNA Dysregulation in Keratinocyte Carcinomas: Clinical Evidence, Experimental Validation, and Future DirectionsSemantic proximity Read ↗

MiRNA-10b marks aggressive squamous cell carcinomas, and confers a cancer stem cell-like phenotypeSemantic proximity Read ↗

Expression of microRNAs in basal cell carcinomaSemantic proximity Read ↗

Downregulation of miR‑637 promotes proliferation and metastasis by targeting Smad3 in keloidsSemantic proximity Read ↗

microRNA-133b downregulation and inhibition of cell proliferation, migration and invasion by targeting matrix metallopeptidase-9 in renal cell carcinomaSemantic proximity Read ↗

MicroRNA‐451a acts as tumor suppressor in cutaneous basal cell carcinomaSemantic proximity Read ↗

MicroRNA-142-5p induces cancer stem cell-like properties of cutaneous squamous cell carcinoma via inhibiting PTEN.Semantic proximity Read ↗

Micro<scp>RNA</scp> expression differs in cutaneous squamous cell carcinomas and healthy skin of immunocompetent individualsSemantic proximity Read ↗

miR-125b Targets ARID3B in Breast Cancer CellsSemantic proximity Read ↗

Induction of Specific MicroRNAs Inhibits Cutaneous Wound HealingSemantic proximity Read ↗

miR-125b induces cellular senescence in malignant melanomaSemantic proximity Read ↗

MiR‐125b inhibits cell biological progression of Ewing's sarcoma by suppressing the PI3K/Akt signalling pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.