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Article

Life stress, the dopamine receptor gene, and emerging adult drug use trajectories: a longitudinal, multilevel, mediated moderation analysis.

Development and psychopathology - 1 Aug 2012

Brody Gene H, Chen Yi-Fu, Yu Tianyi, Beach Steven R H, Kogan Steven M, Simons Ronald L, Windle Michael, Philibert Robert A

Abstract excerpt

This study was designed to examine the prospective relations of life stress and genetic status with increases in drug use. African Americans (N = 399) in rural Georgia (Wave 1 mean age = 17 years) provided three waves of data across 27.5 months and a saliva sample from which the dopamine receptor D4 (DRD4) gene was genotyped. Multilevel growth curve modeling analysis indicated that emerging adults manifested the...

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Source

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Identifiers

PMID: 22781864
DOI: 10.1017/S0954579412000466
PMCID: PMC3395235

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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