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Article

Linkage disequilibrium and demographic history of wild and domestic canids.

Genetics - 1 Apr 2009

Gray Melissa M, Granka Julie M, Bustamante Carlos D, Sutter Nathan B, Boyko Adam R, Zhu Lan, Ostrander Elaine A, Wayne Robert K

Abstract excerpt

Assessing the extent of linkage disequilibrium (LD) in natural populations of a nonmodel species has been difficult due to the lack of available genomic markers. However, with advances in genotyping and genome sequencing, genomic characterization of natural populations has become feasible. Using sequence data and SNP genotypes, we measured LD and modeled the demographic history of wild canid populations and...

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Identifiers

PMID: 19189949
DOI: 10.1534/genetics.108.098830
PMCID: PMC2666515

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