Article
Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.
American journal of respiratory and critical care medicine - 1 Sept 2012
Lugogo Njira L, Hollingsworth John W, Howell Druhan L, Que Loretta G, Francisco Dave, Church Tony D, Potts-Kant Erin N, Ingram Jennifer L, Wang Ying, Jung Sin-Ho, Kraft Monica
Abstract excerpt
RATIONALE: Obesity is associated with increased prevalence and severity of asthma. Adipose tissue macrophages can contribute to the systemic proinflammatory state associated with obesity. However, it remains unknown whether alveolar macrophages have a unique phenotype in overweight/obese patients...
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