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Article

The microRNA cluster C19MC is deregulated in parathyroid tumours

5 Jul 2012

Abstract excerpt

A subset of over-expressed microRNAs (miRNAs) identified in parathyroid carcinomas (Ca) compared to normal glands belongs to C19MC, a cluster on chromosome 19q13.4 involved in stem cell biology and tumourigenesis. In this study, the expression of C19MC-MIR371-3 clusters and the molecular mechanisms presiding their modulation were investigated in a series of six normal parathyroids, 24 adenomas (Ad), 15 Ca and...

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PMID: 22767050
DOI: 10.1530/jme-11-0189

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