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Article

miR-886-3p levels are elevated in Friedreich ataxia.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 4 Jul 2012

Mahishi Lata H, Hart Ronald P, Lynch David R, Ratan Rajiv R

Abstract excerpt

Friedreich ataxia (FRDA) is the most common inherited ataxia caused primarily by an intronic GAA.TTC triplet repeat expansion in the frataxin (FXN) gene. FXN RNA and protein levels are reduced in patients leading to progressive gait and limb ataxia, sensory loss, reduced tendon reflexes, dysarthria, absent lower limb reflexes, and loss of position and vibration sense. Neurological manifestations ensue from...

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Source

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Identifiers

PMID: 22764244
DOI: 10.1523/JNEUROSCI.0059-12.2012
PMCID: PMC4471167

Genes

FXN
GAA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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