Article
The association of vitamin D receptor gene polymorphisms and serum 25-hydroxyvitamin D levels with generalized vitiligo.
The British journal of dermatology - 1 Oct 2012
Li K, Shi Q, Yang L, Li X, Liu L, Wang L, Li Q, Wang G, Li C-Y, Gao T-W
Abstract excerpt
BACKGROUND: Vitiligo is an acquired depigmentation autoimmune disorder that has been described as being associated with lower levels of 25-hydroxyvitamin D [25(OH)D]. Genetic variations within the vitamin D receptor (VDR) gene could lead to significant receptor dysfunction, and could further affect the formation of the biologically active 25(OH)D. Therefore, we hypothesized that VDR polymorphisms might be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.