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Article

Stem Cell-Derived Human Intestinal Organoids as an Infection Model for Rotaviruses

4 Jul 2012

Abstract excerpt

UNLABELLED: Directed differentiation of stem cell lines into intestine-like tissue called induced human intestinal organoids (iHIOs) is now possible (J. R. Spence, C. N. Mayhew, S. A. Rankin, M. F. Kuhar, J. E. Vallance, K. Tolle, E. E. Hoskins, V. V. Kalinichenko, S. I. Wells, A. M. Zorn, N. F. Shroyer, and J. M. Wells, Nature 470:105-109, 2011). We tested iHIOs as a new model to cultivate and study fecal...

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PMID: 22761392
DOI: 10.1128/mbio.00159-12

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