Article
Evolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America - 10 Jul 2012
Hong Zhi, Kajiura Hiroyuki, Su Wei, Jin Hua, Kimura Akihisa, Fujiyama Kazuhito, Li Jianming
Abstract excerpt
Asparagine-linked glycans (N-glycans) are crucial signals for protein folding, quality control, and endoplasmic reticulum (ER)-associated degradation (ERAD) in yeast and mammals. Although similar ERAD processes were reported in plants, little is known about their biochemical mechanisms, especially their relationships with N-glycans. Here, we show that a missense mutation in the Arabidopsis EMS-mutagenized bri1...
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