Article
The Role of SBI2/ALG12/EBS4 in the Regulation of Endoplasmic Reticulum-Associated Degradation (ERAD) Studied by a Null Allele.
International journal of molecular sciences - 22 May 2022
Sun Xiaoxia, Zhao Di, Ali Khawar, Zhu Yumeng, Wu Guang, Li Guishuang
Abstract excerpt
Redundancy and lethality is a long-standing problem in genetics but generating minimal and lethal phenotypes in the knockouts of the same gene by different approaches drives this problem to a new high. In Asn (N)-linked glycosylation, a complex and ubiquitous cotranslational and post-translational protein modification required for the transfer of correctly folded proteins and endoplasmic reticulum-associated...
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