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Article

Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells

21 Jun 2012

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22728882
DOI: 10.1016/j.bbrc.2012.06.075

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Related research

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Click a neighbor to travelStep 1 · 12 closest

Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cellsPMID 22728882Read ↗

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cellsSemantic proximity Read ↗

Down-regulation of NAMPT expression by mir-206 reduces cell survival of breast cancer cellsSemantic proximity Read ↗

Chemical Proteomics Identifies Nampt as the Target of CB30865, An Orphan Cytotoxic CompoundSemantic proximity Read ↗

Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracilSemantic proximity Read ↗

Role for DYRK family kinases on regulation of apoptosisSemantic proximity Read ↗

STAT3 regulated ATR via microRNA-383 to control DNA damage to affect apoptosis in A431 cellsSemantic proximity Read ↗

Salubrinal protects against rotenone-induced SH-SY5Y cell death via ATF4-parkin pathwaySemantic proximity Read ↗

Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferaseSemantic proximity Read ↗

Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid CoadministrationSemantic proximity Read ↗

Suppression of IKK, but not activation of p53 is responsible for cell death mediated by naturally occurring oxidized tetranortriterpenoid.Semantic proximity Read ↗

The NAMPT Inhibitor FK866 in Combination with Cisplatin Reduces Cholangiocarcinoma Cells GrowthSemantic proximity Read ↗

NAMPT-derived NAD <sup>+</sup> fuels PARP1 to promote skin inflammation through parthanatosSemantic proximity Read ↗

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