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Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracil

4 Jul 2011

Abstract excerpt

Nicotinamide phosphoribosyltransferase (Nampt), an enzyme involved in the NAD⁺ salvage pathway, is over-expressed and important in the carcinogenesis in several types of cancers. The expression of Nampt and its role in gastric cancer remain largely unknown. In this study, using real-time PCR and Western blotting we found that Nampt was overexpressed at the mRNA and protein levels, respectively, in established...

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Peptidase Inhibition and Analysis
Signaling Pathways in Disease

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21743967
DOI: 10.3892/or.2011.1378

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Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracilPMID 21743967Read ↗

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