Article
Uninformative polymorphisms bias genome scans for signatures of selection.
BMC evolutionary biology - 22 Jun 2012
Roesti Marius, Salzburger Walter, Berner Daniel
Abstract excerpt
BACKGROUND: With the establishment of high-throughput sequencing technologies and new methods for rapid and extensive single nucleotide (SNP) discovery, marker-based genome scans in search of signatures of divergent selection between populations occupying ecologically distinct environments are becoming increasingly popular. METHODS AND RESULTS: On the basis of genome-wide SNP marker data generated by RAD...
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