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Associations of long interspersed nuclear element-1 DNA methylation with preterm birth in a prospective cohort study

29 Feb 2012

Abstract excerpt

Preterm birth affects over 12% of all infants born in the US yet the biology of early delivery remains unclear, including whether epigenetic mechanisms are involved. We examined associations of maternal and umbilical cord blood long interspersed nuclear element-1 (LINE-1) DNA methylation with length of gestation and odds of preterm birth in singleton pregnancies in Project Viva. In white blood cells from maternal...

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PMID: 22720130
DOI: 10.1017/s2040174412000104

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